The Role of Interoception in Multiple Sclerosis: Clinical Evidence and Rehabilitation Implications

Authors

  • Elena Piscopo Dipartimento di Psicologia, Università degli Studi della Campania “Luigi Vanvitelli”, Caserta, Italia. Autore responsabile per la corrispondenza: ele_piscopo@outlook.it

Keywords:

Multiple sclerosis, Interoception, Fatigue, Metacognition, Rehabilitation

Abstract

Multiple Sclerosis (MS) is a chronic demyelinating disease of the central nervous system that affects motor, cognitive, and emotional domains, with fatigue being among the most debilitating symptoms. Recent evidence suggests that altered interoception—the ability to sense and interpret internal bodily signals—may play a key role in the pathophysiology of fatigue in MS. This article offers an integrative review of interoceptive processes in MS, focusing on their neuroanatomical bases, cognitive correlates, and implications for symptomatology. Finally, has been explore the therapeutic potential of novel interventions—including embodiment-based approaches, transcranial direct current stimulation (tDCS), and virtual reality (VR) focusing on interoceptive and sensorimotor processing to support rehabilitation in MS.

 

doi: 10.53240/2025topic4n2.2.001

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Published

2025-10-20

How to Cite

Piscopo, E. (2025). The Role of Interoception in Multiple Sclerosis: Clinical Evidence and Rehabilitation Implications. TOPIC - Temi Di Psicologia dell’Ordine Degli Psicologi Della Campania, 4(2). Retrieved from https://topic.oprc.it/index.php/topic/article/view/99

Issue

Vol. 4 No. 2 (2025): TOPIC - Temi di Psicologia dell’Ordine degli Psicologi della Campania

Section

Neuropsicologia e neuroscienze

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